Amyloid‐β oligomers suppress subunit‐specific glutamate receptor increase during LTP

Abstract Introduction Amyloid‐β oligomers (AβOs) are assumed to impair the ability of learning and memory by suppressing the induction of synaptic plasticity, such as long‐term potentiation (LTP) in the early stage of Alzheimer's disease. However, the direct molecular mechanism of how AβOs affe...

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Bibliographic Details
Main Authors: Hiromitsu Tanaka, Daiki Sakaguchi, Tomoo Hirano
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Online Access:https://doi.org/10.1016/j.trci.2019.10.003
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