Cirsilineol improves anesthesia/surgery-induced postoperative cognitive dysfunction through attenuating oxidative stress and modulating microglia M1/M2 polarization

Background Cirsilineol is a trimethoxy and dihydroxy flavonoid isolated from plant species such as Artemisia vestita and has a variety of pharmacological properties. This study analyzed whether cirsilineol could prevent postoperative cognitive dysfunction (POCD). Methods A POCD mouse model induced b...

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Bibliographic Details
Main Authors: Junli Du, Chao Chen, Jie Chen
Format: Article
Language:English
Published: PeerJ Inc. 2024-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/18507.pdf
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