Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaques.

Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaques.

Understanding the genetic, antigenic and structural changes that occur during HIV-1 infection in response to pre-existing immunity will facilitate current efforts to develop an HIV-1 vaccine. Much is known about HIV-1 variation at the population level but little with regard to specific changes occur...

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Main Authors: Mariana Varela, Ernst Verschoor, Rachel P J Lai, Joseph Hughes, Petra Mooj, Trevelyan J McKinley, Timothy J Fitzmaurice, Lisa Landskron, Brian J Willett, Simon D W Frost, Willy M Bogers, Jonathan L Heeney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0070814&type=printable
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