Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature
Malignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022, with new cases expected to rise to 35 million annually by 2050. Immunotherapy is preferred to other cancer therapies, offering precise targeting...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2024/8481761 |
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| _version_ | 1841524381298196480 |
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| author | Angus Nnamdi Oli Samson Adedeji Adejumo Adekunle Babajide Rowaiye Joyce Oloaigbe Ogidigo Jarrad Hampton-Marcell Gordon C. Ibeanu |
| author_facet | Angus Nnamdi Oli Samson Adedeji Adejumo Adekunle Babajide Rowaiye Joyce Oloaigbe Ogidigo Jarrad Hampton-Marcell Gordon C. Ibeanu |
| author_sort | Angus Nnamdi Oli |
| collection | DOAJ |
| description | Malignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022, with new cases expected to rise to 35 million annually by 2050. Immunotherapy is preferred to other cancer therapies, offering precise targeting of malignant cells while simultaneously strengthening the immune system’s complex responses. Advances in this novel field of science have been closely linked to a deeper knowledge of tumor biology, particularly the intricate interplay between tumor cells, the immune system, and the tumor microenvironment (TME), which are central to cancer progression and immune evasion. This review offers a comprehensive analysis of the molecular mechanisms that govern these interactions, emphasizing their critical role in the development of effective immunotherapeutic products. We critically evaluate the current immunotherapy approaches, including cancer vaccines, adoptive T cell therapies, and cytokine-based treatments, highlighting their efficacy and safety. We also explore the latest advancements in combination therapies, which synergistically integrate multiple immunotherapeutic strategies to overcome resistance and enhance therapeutic outcomes. This review offers key insights into the future of cancer immunotherapy with a focus on advancing more effective and personalized treatment strategies. |
| format | Article |
| id | doaj-art-bec09172912945ed869550fff8253fe7 |
| institution | Kabale University |
| issn | 2314-7156 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-bec09172912945ed869550fff8253fe72025-02-03T07:21:40ZengWileyJournal of Immunology Research2314-71562024-01-01202410.1155/2024/8481761Tumour Immunotherapy and Applications of Immunological Products: A Review of LiteratureAngus Nnamdi Oli0Samson Adedeji Adejumo1Adekunle Babajide Rowaiye2Joyce Oloaigbe Ogidigo3Jarrad Hampton-Marcell4Gordon C. Ibeanu5Department of Pharmaceutical Microbiology and BiotechnologyDepartment of Biological SciencesNational Biotechnology Development AgencyNational Biotechnology Development AgencyDepartment of Biological SciencesDepartment of Pharmaceutical ScienceMalignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022, with new cases expected to rise to 35 million annually by 2050. Immunotherapy is preferred to other cancer therapies, offering precise targeting of malignant cells while simultaneously strengthening the immune system’s complex responses. Advances in this novel field of science have been closely linked to a deeper knowledge of tumor biology, particularly the intricate interplay between tumor cells, the immune system, and the tumor microenvironment (TME), which are central to cancer progression and immune evasion. This review offers a comprehensive analysis of the molecular mechanisms that govern these interactions, emphasizing their critical role in the development of effective immunotherapeutic products. We critically evaluate the current immunotherapy approaches, including cancer vaccines, adoptive T cell therapies, and cytokine-based treatments, highlighting their efficacy and safety. We also explore the latest advancements in combination therapies, which synergistically integrate multiple immunotherapeutic strategies to overcome resistance and enhance therapeutic outcomes. This review offers key insights into the future of cancer immunotherapy with a focus on advancing more effective and personalized treatment strategies.http://dx.doi.org/10.1155/2024/8481761 |
| spellingShingle | Angus Nnamdi Oli Samson Adedeji Adejumo Adekunle Babajide Rowaiye Joyce Oloaigbe Ogidigo Jarrad Hampton-Marcell Gordon C. Ibeanu Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature Journal of Immunology Research |
| title | Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature |
| title_full | Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature |
| title_fullStr | Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature |
| title_full_unstemmed | Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature |
| title_short | Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature |
| title_sort | tumour immunotherapy and applications of immunological products a review of literature |
| url | http://dx.doi.org/10.1155/2024/8481761 |
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