Structural modeling of ion channels using AlphaFold2, RoseTTAFold2, and ESMFold
Ion channels play key roles in human physiology and are important targets in drug discovery. The atomic-scale structures of ion channels provide invaluable insights into a fundamental understanding of the molecular mechanisms of channel gating and modulation. Recent breakthroughs in deep learning-ba...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | Channels |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19336950.2024.2325032 |
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