Integrative analysis of gut microbiome and host transcriptome reveal novel molecular signatures in Hashimoto's thyroiditis

Integrative analysis of gut microbiome and host transcriptome reveal novel molecular signatures in Hashimoto's thyroiditis

Abstract Background Hashimoto's thyroiditis (HT) is an autoimmune disorder with unclear molecular mechanisms. While current diagnosis is well-established, understanding of the gut-thyroid axis in HT remains limited. This study aimed to uncover novel molecular signatures in HT by integrating gut...

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Bibliographic Details
Main Authors: Miao Li, Ke Chen, Yuqi Chen, Lei Zhang, Yipeng Cui, Fengxu Xiao, Zhenting Liu, Wen Zhang, Jue jiang, Qi Zhou, Jiangwei Yan, Yu Sun, Fanglin Guan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Gut microbiome
Gut-thyroid axis
Hashimoto's thyroiditis
Integrative analysis
Molecular signatures
Transcriptome
Online Access:https://doi.org/10.1186/s12967-024-05876-3
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