Targeting ferroptosis in cancer stem cells: A novel strategy to improve cancer treatment

Targeting ferroptosis in cancer stem cells: A novel strategy to improve cancer treatment

Ferroptosis, a distinct regulated cell death process characterized by iron retention and lipid peroxidation, plays a crucial role in the survival of cancer stem cells (CSCs), key contributors to cancer initiation, progression, and recurrence. CSCs exhibit enhanced iron uptake and altered lipid metab...

Full description

Saved in:
Bibliographic Details
Main Authors: Luyao Wang, Ye Zhu, Chengying Huang, Qiuming Pan, Junxi Wang, Hongrui Li, Yudi Huang, Guozhong Yi, Zhiyong Li, Songtao Qi, Guanglong Huang, Shanqiang Qu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-11-01
Series:Genes and Diseases
Subjects:
Cancer stemcells (CSCs)
Cell signaling
Drug target
Ferroptosis
Iron metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304225001679
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2352304225001679

Similar Items