Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals
Objective: The objective of the research was to ascertain whether serum levels of the biochemical markers adiponectin and leptin are related to clinical periodontal characteristics. Materials and Method: For the study, 20 people with chronic periodontitis (Group A) and 20 healthy people (Group B) we...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1355_24 |
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| author | Reghunathan S. Preethanath Swaroop Chandy Nubesh Khan Syed Bugude Shiva Shankar Pavithra Rangarajan Seshadri R Narayane P. K. Saraswathi Bai |
| author_facet | Reghunathan S. Preethanath Swaroop Chandy Nubesh Khan Syed Bugude Shiva Shankar Pavithra Rangarajan Seshadri R Narayane P. K. Saraswathi Bai |
| author_sort | Reghunathan S. Preethanath |
| collection | DOAJ |
| description | Objective:
The objective of the research was to ascertain whether serum levels of the biochemical markers adiponectin and leptin are related to clinical periodontal characteristics.
Materials and Method:
For the study, 20 people with chronic periodontitis (Group A) and 20 healthy people (Group B) were enrolled. Assessments were conducted on periodontal markers, including bleeding on probing (POP), gingival index (GI), plaque index (PI), probing pocket depth (PPD), and clinical attachment level (CAL). An enzyme-linked immunosorbent assay (ELISA) test was used to assess the levels of adiponectin and leptin in serum samples.
Result:
There was significant elevation in average level of leptin in chronic periodontitis in association to that in healthy group. On the other hand, there was considerable decrease in serum adiponectin in group A in association to healthy group. The ratio of leptin\adiponectin was appreciably greater amongst periodontitis group compared to healthy group.
Conclusion:
The current investigation leads us to the conclusion that the pathophysiology of periodontitis is significantly influenced by serum levels of adiponectin and leptin. |
| format | Article |
| id | doaj-art-bdfb69bfc8d94967b9ea97a98f0339bb |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-bdfb69bfc8d94967b9ea97a98f0339bb2025-01-13T10:37:05ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3887S388910.4103/jpbs.jpbs_1355_24Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy IndividualsReghunathan S. PreethanathSwaroop ChandyNubesh Khan SyedBugude Shiva ShankarPavithra Rangarajan SeshadriR NarayaneP. K. Saraswathi BaiObjective: The objective of the research was to ascertain whether serum levels of the biochemical markers adiponectin and leptin are related to clinical periodontal characteristics. Materials and Method: For the study, 20 people with chronic periodontitis (Group A) and 20 healthy people (Group B) were enrolled. Assessments were conducted on periodontal markers, including bleeding on probing (POP), gingival index (GI), plaque index (PI), probing pocket depth (PPD), and clinical attachment level (CAL). An enzyme-linked immunosorbent assay (ELISA) test was used to assess the levels of adiponectin and leptin in serum samples. Result: There was significant elevation in average level of leptin in chronic periodontitis in association to that in healthy group. On the other hand, there was considerable decrease in serum adiponectin in group A in association to healthy group. The ratio of leptin\adiponectin was appreciably greater amongst periodontitis group compared to healthy group. Conclusion: The current investigation leads us to the conclusion that the pathophysiology of periodontitis is significantly influenced by serum levels of adiponectin and leptin.https://journals.lww.com/10.4103/jpbs.jpbs_1355_24adiponectinchronic preiodontitisleptinobese individualsoral healthperiodontal diseasessaliva |
| spellingShingle | Reghunathan S. Preethanath Swaroop Chandy Nubesh Khan Syed Bugude Shiva Shankar Pavithra Rangarajan Seshadri R Narayane P. K. Saraswathi Bai Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals Journal of Pharmacy and Bioallied Sciences adiponectin chronic preiodontitis leptin obese individuals oral health periodontal diseases saliva |
| title | Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals |
| title_full | Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals |
| title_fullStr | Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals |
| title_full_unstemmed | Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals |
| title_short | Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals |
| title_sort | assessment of serum adiponectin and leptin in chronic periodontitis over healthy individuals |
| topic | adiponectin chronic preiodontitis leptin obese individuals oral health periodontal diseases saliva |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_1355_24 |
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