The impact of rs6198 genotyping of glucocorticoid b-receptor gene in sepsis
BACKGROUND: Glucocorticosteroids (GCs) are used for the treatment of sepsis, while their role is mediated exclusively by the glucocorticoid receptor (GR) and its gene NR3C1. The rs6198 single-nucleotide polymorphism (SNP), localized in exon 9β of the NR3C1, has been shown to increase GC sensitivity....
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Journal of Global Antimicrobial Resistance |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213716524003400 |
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