RGS1 stabilized by METTL3-mediated m6A modification promotes the tumorigenicity and macrophage M2 polarization in osteosarcoma

Background: Regulators of G-protein signaling 1 (RGS1) has been reported to be involved in immune cell regulation in many cancer types. However, the specific role and mechanism in osteosarcoma (OS) progression and macrophage activation remain unclear. Methods: Levels of mRNA and protein were examine...

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Bibliographic Details
Main Authors: Zhizhong Liang, Yuxia Shi, Mao Wang, Liqiang Zhang
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Journal of Bone Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212137425000466
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