PGRN protects against serum deprivation-induced cell death by promoting the ROS scavenger system in cervical cancer

Abstract Progranulin (PGRN), an autocrine growth factor with tumorigenic roles in a variety of tumors, is a putative survival factor for normal and cancer cells in vitro. However, the fundamental mechanism of PGRN-mediated survival of cancer cells suffering from various types of microenvironmental s...

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Bibliographic Details
Main Authors: Tingting Feng, Xiaoying Xu, Xiao Wang, Wei Tang, Yi Lu
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07233-0
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