Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational study
Background and Objective: Respiratory distress is the most common cause requiring neonatal intensive care unit admission. As respiratory and cardiac functions are closely interrelated, some cardiac dysfunction is expected in respiratory distress. The myocardial performance index (MPI) is an index to...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
|
| Series: | Annals of Pediatric Cardiology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/apc.apc_167_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841554802722471936 |
|---|---|
| author | Nikita Panigrahi Harohalli A. Venkatesh Manas Ranjan Mishra Rajath Pejaver Karthik N. Nagesh |
| author_facet | Nikita Panigrahi Harohalli A. Venkatesh Manas Ranjan Mishra Rajath Pejaver Karthik N. Nagesh |
| author_sort | Nikita Panigrahi |
| collection | DOAJ |
| description | Background and Objective:
Respiratory distress is the most common cause requiring neonatal intensive care unit admission. As respiratory and cardiac functions are closely interrelated, some cardiac dysfunction is expected in respiratory distress. The myocardial performance index (MPI) is an index to assess global myocardial function, easily measurable by bedside echocardiography and reliable. Here, we conducted this study to determine the change in cardiac function in neonates with respiratory distress before initiating respiratory support and after weaning from the support.
Methodology:
The study was carried out in 92 neonates with a gestational age of more than 32 weeks who required invasive or noninvasive respiratory support. The tissue Doppler left ventricular MPI (LV MPI) was calculated before the initiation of respiratory support and after weaning from respiratory support. The data were analyzed using a paired t-test and a Wilcoxon signed-rank test.
Results:
This study comprised 92 neonates with a median (interquartile range) LV MPI value of 0.56 (0.10) before initiation of respiratory support and 0.47 (0.04) after weaning from respiratory support with P < 0.001. The isovolumetric contraction time, isovolumetric relaxation time, and ejection time increased after weaning from respiratory support (all P < 0.0001). The severity of respiratory distress determined by invasive mode of ventilation and longer duration of respiratory support caused higher initial LV MPI before initiation of respiratory support compared with recovery and P < 0.001, suggesting subclinical ventricular dysfunction with respiratory distress in neonates.
Conclusion:
LV MPI was higher in neonates with respiratory distress and normalized after weaning from respiratory support, which indicates that neonates requiring respiratory support may have subclinical ventricular dysfunction and should be followed up carefully. |
| format | Article |
| id | doaj-art-bd788c54d7344a1c9fc9a3c071d330d5 |
| institution | Kabale University |
| issn | 0974-2069 0974-5149 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Pediatric Cardiology |
| spelling | doaj-art-bd788c54d7344a1c9fc9a3c071d330d52025-01-08T09:25:28ZengWolters Kluwer Medknow PublicationsAnnals of Pediatric Cardiology0974-20690974-51492024-12-0117533133810.4103/apc.apc_167_24Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational studyNikita PanigrahiHarohalli A. VenkateshManas Ranjan MishraRajath PejaverKarthik N. NageshBackground and Objective: Respiratory distress is the most common cause requiring neonatal intensive care unit admission. As respiratory and cardiac functions are closely interrelated, some cardiac dysfunction is expected in respiratory distress. The myocardial performance index (MPI) is an index to assess global myocardial function, easily measurable by bedside echocardiography and reliable. Here, we conducted this study to determine the change in cardiac function in neonates with respiratory distress before initiating respiratory support and after weaning from the support. Methodology: The study was carried out in 92 neonates with a gestational age of more than 32 weeks who required invasive or noninvasive respiratory support. The tissue Doppler left ventricular MPI (LV MPI) was calculated before the initiation of respiratory support and after weaning from respiratory support. The data were analyzed using a paired t-test and a Wilcoxon signed-rank test. Results: This study comprised 92 neonates with a median (interquartile range) LV MPI value of 0.56 (0.10) before initiation of respiratory support and 0.47 (0.04) after weaning from respiratory support with P < 0.001. The isovolumetric contraction time, isovolumetric relaxation time, and ejection time increased after weaning from respiratory support (all P < 0.0001). The severity of respiratory distress determined by invasive mode of ventilation and longer duration of respiratory support caused higher initial LV MPI before initiation of respiratory support compared with recovery and P < 0.001, suggesting subclinical ventricular dysfunction with respiratory distress in neonates. Conclusion: LV MPI was higher in neonates with respiratory distress and normalized after weaning from respiratory support, which indicates that neonates requiring respiratory support may have subclinical ventricular dysfunction and should be followed up carefully.https://journals.lww.com/10.4103/apc.apc_167_24left ventricular myocardial performance indexneonaterespiratory distress |
| spellingShingle | Nikita Panigrahi Harohalli A. Venkatesh Manas Ranjan Mishra Rajath Pejaver Karthik N. Nagesh Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational study Annals of Pediatric Cardiology left ventricular myocardial performance index neonate respiratory distress |
| title | Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational study |
| title_full | Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational study |
| title_fullStr | Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational study |
| title_full_unstemmed | Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational study |
| title_short | Comparing the tissue Doppler-derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates: A prospective observational study |
| title_sort | comparing the tissue doppler derived left ventricular myocardial performance index before and after recovery from respiratory distress in neonates a prospective observational study |
| topic | left ventricular myocardial performance index neonate respiratory distress |
| url | https://journals.lww.com/10.4103/apc.apc_167_24 |
| work_keys_str_mv | AT nikitapanigrahi comparingthetissuedopplerderivedleftventricularmyocardialperformanceindexbeforeandafterrecoveryfromrespiratorydistressinneonatesaprospectiveobservationalstudy AT harohalliavenkatesh comparingthetissuedopplerderivedleftventricularmyocardialperformanceindexbeforeandafterrecoveryfromrespiratorydistressinneonatesaprospectiveobservationalstudy AT manasranjanmishra comparingthetissuedopplerderivedleftventricularmyocardialperformanceindexbeforeandafterrecoveryfromrespiratorydistressinneonatesaprospectiveobservationalstudy AT rajathpejaver comparingthetissuedopplerderivedleftventricularmyocardialperformanceindexbeforeandafterrecoveryfromrespiratorydistressinneonatesaprospectiveobservationalstudy AT karthiknnagesh comparingthetissuedopplerderivedleftventricularmyocardialperformanceindexbeforeandafterrecoveryfromrespiratorydistressinneonatesaprospectiveobservationalstudy |