Optimized chelator and nanoparticle strategies for high-activity 103Pd-loaded biodegradable brachytherapy seeds

Optimized chelator and nanoparticle strategies for high-activity 103Pd-loaded biodegradable brachytherapy seeds

Abstract Background Brachytherapy (BT) is routinely used in the treatment of various cancers. Current BT relies on the placement of large sources of radioactivity at the tumor site, requiring applicators that may cause local traumas and lesions. Further, they suffer from inflexibility in where they...

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Bibliographic Details
Main Authors: Emanuel Sporer, Claire Deville, Natan J. W. Straathof, Linda M. Bruun, Ulli Köster, Mikael Jensen, Thomas L. Andresen, Paul J. Kempen, Jonas R. Henriksen, Andreas I. Jensen
Format: Article
Language:English
Published: SpringerOpen 2024-12-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Brachytherapy
Palladium-103
Auger radiotherapy
Radiochemistry
Gold nanoparticles
Biodegradable gels
Online Access:https://doi.org/10.1186/s41181-024-00309-4
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https://doi.org/10.1186/s41181-024-00309-4

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