“Hydroethanol extract and triterpenoids of Senegalia ataxacantha show antiplasmodial activity and the compounds are predicted to inhibit parasite lactate dehydrogenase (pfLDH) as indicated by molecular docking studies”

“Hydroethanol extract and triterpenoids of Senegalia ataxacantha show antiplasmodial activity and the compounds are predicted to inhibit parasite lactate dehydrogenase (pfLDH) as indicated by molecular docking studies”

Malaria claims over 600,000 deaths annually with a disproportionately high burden in the WHO African Region. The development of parasite resistance has warranted the search for novel anti-plasmodial drug candidates. This research aimed at validating the efficacy of Senegalia ataxacantha and tracking...

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Bibliographic Details
Main Authors: Kennedy Ameyaw Baah, Akwasi Acheampong, Isaac Kingsley Amponsah, Silas Adjei, Yakubu Jibira, Reinhard Isaac Nketia, Linda Mensah Sarpong, Emmanuel Quaye Kontoh
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Scientific African
Subjects:
Antipyretic
In silico
Structural elucidation
Chromatographic fractionation
Antimalaria
Pharmacokinetic profile
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227624003971
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