Hydrogen Sulfide and Gut Microbiota: Their Synergistic Role in Modulating Sirtuin Activity and Potential Therapeutic Implications for Neurodegenerative Diseases

Hydrogen Sulfide and Gut Microbiota: Their Synergistic Role in Modulating Sirtuin Activity and Potential Therapeutic Implications for Neurodegenerative Diseases

The intricate relationship between hydrogen sulfide (H<sub>2</sub>S), gut microbiota, and sirtuins (SIRTs) can be seen as a paradigm axis in maintaining cellular homeostasis, modulating oxidative stress, and promoting mitochondrial health, which together play a pivotal role in aging and...

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Bibliographic Details
Main Authors: Constantin Munteanu, Gelu Onose, Mădălina Poștaru, Marius Turnea, Mariana Rotariu, Anca Irina Galaction
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
sirtuins
hydrogen sulfide
gut microbiota
pharmacological intervention
neurodegenerative diseases
Online Access:https://www.mdpi.com/1424-8247/17/11/1480
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