Celastrol loaded nanocomplex for painless tumor therapy via YAP inhibition

Celastrol loaded nanocomplex for painless tumor therapy via YAP inhibition

Abstract Cancer-related pain is prevalent and severely impairs patients’ quality of life. However, conventional cancer therapies primarily target tumor cell destruction, often overlooking the management of cancer pain. Thus, there is an immediate necessity to develop therapeutic agents that can both...

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Main Authors: Zhaokun Hao, Yuming Zhou, Yuqiang Zhang, Danyang Wang, Yiying Wei, Xiaopu Ji, Wan Ru Sun, Pingyu Wang, YouJie Li, Irene Bautista Lopez, José Luis Pedraz, Murugan Ramalingam, Shuyang Xie, Ranran Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Celastrol
Nanocomposite
Cancer pain supression
Immunotherapy
YAP Inhibition
Online Access:https://doi.org/10.1038/s41598-025-97055-7
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https://doi.org/10.1038/s41598-025-97055-7

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