Prognostic impact of circulating tumor DNA detection in portal and peripheral blood in resected pancreatic ductal adenocarcinoma patients

Prognostic impact of circulating tumor DNA detection in portal and peripheral blood in resected pancreatic ductal adenocarcinoma patients

Abstract In PDAC patients, ctDNA detection’s prognostic significance needs validation especially in resected patients. This study investigated ctDNA kinetics in portal and peripheral blood before and after resection, and whether tissue mobilization during surgery influences ctDNA detection. In this...

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Main Authors: Charlotte Maulat, Cindy Canivet, Bastien Cabarrou, Anne Pradines, Janick Selves, Anne Casanova, Aurélia Doussine, Naïma Hanoun, Emmanuel Cuellar, Paul Boulard, Nicolas Carrère, Louis Buscail, Barbara Bournet, Fabrice Muscari, Pierre Cordelier
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Circulating tumor DNA
Pancreatic ductal adenocarcinoma
Liquid biopsy
Overall survival
Recurrence-free survival
Tissue mobilization
Online Access:https://doi.org/10.1038/s41598-024-76903-y
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https://doi.org/10.1038/s41598-024-76903-y

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