ZBP1 senses Brucella abortus DNA triggering type I interferon signaling pathway and unfolded protein response activation

ZBP1 senses Brucella abortus DNA triggering type I interferon signaling pathway and unfolded protein response activation

The innate immune system promptly detects and responds to invading pathogens, with a key role played by the recognition of bacterial-derived DNA through pattern recognition receptors. The Z-DNA binding protein 1 (ZBP1) functions as a DNA sensor inducing type I interferon (IFN) production, innate imm...

Full description

Saved in:
Bibliographic Details
Main Authors: Marco Túlio R. Gomes, Erika S. Guimarães, Sergio C. Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
Brucella abortus
macrophage
type I interferon
upr
ZBP1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1511949/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items