Hierarchical marker genes selection in scRNA-seq analysis.

When analyzing scRNA-seq data containing heterogeneous cell populations, an important task is to select informative marker genes to distinguish various cell clusters and annotate the clusters with biologically meaningful cell types. In existing analysis methods and pipelines, marker genes are typica...

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Bibliographic Details
Main Authors: Yutong Sun, Peng Qiu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012643
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