From gut to proteomics: the impact of Roseburia intestinalis on post-translational modifications in colorectal cancer

From gut to proteomics: the impact of Roseburia intestinalis on post-translational modifications in colorectal cancer

BackgroundColorectal cancer (CRC) represents a significant global health challenge. Gut microbiota imbalance and abnormal chromatin modifications play critical roles in the progression of CRC. However, the mechanisms by which they exert their influences, particularly the involvement of Roseburia int...

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Bibliographic Details
Main Authors: Lu Li, Yong Zhang, Qianqian Wu, Ziyu Jin, Hongbing Xia, Huili Wu, Kunkun Li, Lihong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
Roseburia intestinalis
global proteomics
acetylation
lactylation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1599183/full
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