HSD17B7 gene in self‐renewal and oncogenicity of keratinocytes from Black versus White populations

HSD17B7 gene in self‐renewal and oncogenicity of keratinocytes from Black versus White populations

Abstract Human populations of Black African ancestry have a relatively high risk of aggressive cancer types, including keratinocyte‐derived squamous cell carcinomas (SCCs). We show that primary keratinocytes (HKCs) from Black African (Black) versus White Caucasian (White) individuals have on average...

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Bibliographic Details
Main Authors: Xiaoying Xu, Beatrice Tassone, Paola Ostano, Atul Katarkar, Tatiana Proust, Jean‐Marc Joseph, Chiara Riganti, Giovanna Chiorino, Zoltan Kutalik, Karine Lefort, Gian Paolo Dotto
Format: Article
Language:English
Published: Springer Nature 2021-06-01
Series:EMBO Molecular Medicine
Subjects:
genetic cancer susceptibility
HSD enzymes
OXPHOS
squamous cell carcinoma
stem cell potential
Online Access:https://doi.org/10.15252/emmm.202114133
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https://doi.org/10.15252/emmm.202114133

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