Neuroinflammation and hypoxia promote astrocyte phenotypic transformation and propel neurovascular dysfunction in brain arteriovenous malformation

Neuroinflammation and hypoxia promote astrocyte phenotypic transformation and propel neurovascular dysfunction in brain arteriovenous malformation

Abstract Brain arteriovenous malformation (BAVM) is a complex cerebrovascular disease characterized by an abnormal high-flow vascular network, which increases the risk of hemorrhage, particularly in young individuals. Endothelial dysfunction has traditionally been considered the primary cause, while...

Full description

Saved in:
Bibliographic Details
Main Authors: Tianqi Tu, Zhenghong Peng, Lihan Zhang, Jieru Yang, Kecheng Guo, Xiaogang Tang, Jiasen Ye, Fan Zhang, An Huang, Jiaxing Yu, Changren Huang, Hongqi Zhang, Donghai Wang, Jianhua Peng, Yong Jiang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Neuroinflammation
Subjects:
Brain arteriovenous malformation
Astrocytes
Neuroinflammation
Hypoxia
Cyclooxygenase-2
Online Access:https://doi.org/10.1186/s12974-025-03442-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12974-025-03442-2

Similar Items