A map of human cancer signaling
Abstract We conducted a comprehensive analysis of a manually curated human signaling network containing 1634 nodes and 5089 signaling regulatory relations by integrating cancer‐associated genetically and epigenetically altered genes. We find that cancer mutated genes are enriched in positive signali...
Saved in:
| Main Authors: | Qinghua Cui, Yun Ma, Maria Jaramillo, Hamza Bari, Arif Awan, Song Yang, Simo Zhang, Lixue Liu, Meng Lu, Maureen O'Connor‐McCourt, Enrico O Purisima, Edwin Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2007-12-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb4100200 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Modern strategies for study of tumor’s markers in clinical practic
by: I. B. Zborovskaya
Published: (2015-06-01) -
Protocol for tandem enrichment of ubiquitinated, phosphorylated, and glycosylated peptides with SCASP-PTM
by: Zhan-Peng Lin, et al.
Published: (2025-09-01) -
Network quantification of EGFR signaling unveils potential for targeted combination therapy
by: Bertram Klinger, et al.
Published: (2013-06-01) -
Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway
by: Bryan W Miller, et al.
Published: (2009-10-01) -
Mutational landscape and DNA methylation-based classification of squamous cell carcinoma and urothelial carcinoma
by: Min Ren, et al.
Published: (2025-06-01)