Copper oxide nanoparticles exacerbate chronic obstructive pulmonary disease by activating the TXNIP-NLRP3 signaling pathway

Copper oxide nanoparticles exacerbate chronic obstructive pulmonary disease by activating the TXNIP-NLRP3 signaling pathway

Abstract Background Although copper oxide nanoparticles (CuONPs) offer certain benefits to humans, they can be toxic to organs and exacerbate underlying diseases upon exposure. Chronic obstructive pulmonary disease (COPD), induced by smoking, can worsen with exposure to various harmful particles. Ho...

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Main Authors: Woong-Il Kim, So-Won Pak, Se-Jin Lee, Sin-Hyang Park, Je-Oh Lim, Dong-il Kim, In-Sik Shin, Sung-Hwan Kim, Jong-Choon Kim
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Particle and Fibre Toxicology
Subjects:
Copper oxide nanoparticles
Chronic obstructive pulmonary disease
Thioredoxin-interacting protein
NOD-like receptor protein 3
Inflammation
Online Access:https://doi.org/10.1186/s12989-024-00608-3
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https://doi.org/10.1186/s12989-024-00608-3

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