Rapamycin treatment for Alzheimer’s disease and related dementias: a pilot phase 1 clinical trial

Rapamycin treatment for Alzheimer’s disease and related dementias: a pilot phase 1 clinical trial

Abstract Background Rapamycin has been shown to extend lifespan and acts on pathologies underlying Alzheimer’s disease and related dementias in animal models. However, rapamycin’s clinical application remains underexplored. Methods We conducted a single-site open-label phase 1 clinical trial (Clinic...

Full description

Saved in:
Bibliographic Details
Main Authors: Mitzi M. Gonzales, Valentina R. Garbarino, Tiffany F. Kautz, Xuemei Song, Marisa Lopez-Cruzan, Leslie Linehan, Candice E. Van Skike, Gabriel A. De Erausquin, Veronica Galvan, Miranda E. Orr, Nicolas Musi, Yingxin He, Randall J. Bateman, Chen-Pin Wang, Sudha Seshadri, Ellen Kraig, Dean Kellogg
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00904-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s43856-025-00904-9

Similar Items