Allele frequency in thyroid cancer: mechanisms, challenges, and applications in cancer therapy

Abstract Allele Frequency (AF) is the percentage of sequence reads with a specific mutation relative to the read depth at that locus, reflecting the proportion of gene mutation. This review explores the AF characteristics of different mutations in thyroid cancer, investigating their connection with...

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Bibliographic Details
Main Authors: Jiayu Huang, Jiazhi Wang, Guangzhi Wang, Yongfu Zhao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Thyroid Research
Subjects:
Online Access:https://doi.org/10.1186/s13044-025-00237-8
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