Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis.
The bacterial second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP) has emerged as a central regulator for biofilm formation. Increased cellular c-di-GMP levels lead to stable cell attachment, which in Pseudomonas fluorescens requires the transmembrane receptor Lap...
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Main Authors: | Marcos V A S Navarro, Peter D Newell, Petya V Krasteva, Debashree Chatterjee, Dean R Madden, George A O'Toole, Holger Sondermann |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-02-01
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Series: | PLoS Biology |
Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000588&type=printable |
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