Mitochondria-targeted therapy with metformin and MitoQ reduces oxidative stress, improves mitochondrial function, and restores metabolic homeostasis in a murine model of Gulf War Illness
Gulf War Illness (GWI) is a cluster of medically unexplained chronic symptoms, including neurological and gastrointestinal impairments, and muscle fatigue, suffered by veterans of the Persian Gulf War. A GWI model in C57BL/6 mice exposed to the nerve gas prophylactic pyridostigmine-bromide (PB) and...
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| Main Authors: | Lun Cai, Mundanattu Swetha, Abraham Raji, Alvin V. Terry, Jr., Raghavan Pillai Raju |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Redox Biology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231725002277 |
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