Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems
Objective: To compare the antimicrobial effectiveness of erbium-doped yttrium-aluminum-garnet (Er: YAG) laser, ozone therapy, photodynamic therapy (PDT), and sodium hypochlorite against endodontic pathogens. Methods: Standardized root canal models inoculated with Enterococcus faecalis, Pseudomonas a...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1116_24 |
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| author | Hitesh Chohan Sanjana Khullar Ria H Patel Jyotirmayee Rath Sameera Mohammed Savadamoorthi Kamatchi Subramani |
| author_facet | Hitesh Chohan Sanjana Khullar Ria H Patel Jyotirmayee Rath Sameera Mohammed Savadamoorthi Kamatchi Subramani |
| author_sort | Hitesh Chohan |
| collection | DOAJ |
| description | Objective:
To compare the antimicrobial effectiveness of erbium-doped yttrium-aluminum-garnet (Er: YAG) laser, ozone therapy, photodynamic therapy (PDT), and sodium hypochlorite against endodontic pathogens.
Methods:
Standardized root canal models inoculated with Enterococcus faecalis, Pseudomonas aeruginosa, and Candida albicans were treated with Er: YAG laser, 5.25% NaOCl, ozone, or PDT with methylene blue. Microbial loads, treatment time, and depth of penetration were assessed.
Results:
Er: YAG laser demonstrated the highest efficacy against Enterococcus faecalis and Pseudomonas aeruginosa, followed by PDT. Effects on Candida albicans were not statistically significant across treatments. Er: YAG achieved the greatest depth of penetration, while PDT required the longest application time.
Conclusions:
Laser and photodynamic therapies show promise as alternatives to traditional chemical disinfection in endodontics, potentially improving treatment outcomes. Further research is needed to optimize these protocols for clinical use. |
| format | Article |
| id | doaj-art-b8d66ed304d141a18539ee11724bc351 |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-b8d66ed304d141a18539ee11724bc3512025-01-13T10:07:33ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3577S357910.4103/jpbs.jpbs_1116_24Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal SystemsHitesh ChohanSanjana KhullarRia H PatelJyotirmayee RathSameera MohammedSavadamoorthi Kamatchi SubramaniObjective: To compare the antimicrobial effectiveness of erbium-doped yttrium-aluminum-garnet (Er: YAG) laser, ozone therapy, photodynamic therapy (PDT), and sodium hypochlorite against endodontic pathogens. Methods: Standardized root canal models inoculated with Enterococcus faecalis, Pseudomonas aeruginosa, and Candida albicans were treated with Er: YAG laser, 5.25% NaOCl, ozone, or PDT with methylene blue. Microbial loads, treatment time, and depth of penetration were assessed. Results: Er: YAG laser demonstrated the highest efficacy against Enterococcus faecalis and Pseudomonas aeruginosa, followed by PDT. Effects on Candida albicans were not statistically significant across treatments. Er: YAG achieved the greatest depth of penetration, while PDT required the longest application time. Conclusions: Laser and photodynamic therapies show promise as alternatives to traditional chemical disinfection in endodontics, potentially improving treatment outcomes. Further research is needed to optimize these protocols for clinical use.https://journals.lww.com/10.4103/jpbs.jpbs_1116_24antimicrobial efficacyendodontic disinfectioner: yag laserozone therapyphotodynamic therapyroot canal treatmentsodium hypochlorite |
| spellingShingle | Hitesh Chohan Sanjana Khullar Ria H Patel Jyotirmayee Rath Sameera Mohammed Savadamoorthi Kamatchi Subramani Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems Journal of Pharmacy and Bioallied Sciences antimicrobial efficacy endodontic disinfection er: yag laser ozone therapy photodynamic therapy root canal treatment sodium hypochlorite |
| title | Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems |
| title_full | Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems |
| title_fullStr | Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems |
| title_full_unstemmed | Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems |
| title_short | Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems |
| title_sort | investigations of the antimicrobial effectiveness of different disinfection protocols against endodontic pathogens in root canal systems |
| topic | antimicrobial efficacy endodontic disinfection er: yag laser ozone therapy photodynamic therapy root canal treatment sodium hypochlorite |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_1116_24 |
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