Exchange of the l-cysteine exporter after in-vivo metabolic control analysis improved the l-cysteine production process with engineered Escherichia coli

Abstract Background l-Cysteine is a proteinogenic amino acid of high pharmaceutical and industrial interest. However, the fermentation process for l-cysteine production is faced with multiple obstacles, like the toxicity of l-cysteine for the cells, the low carbon yield of the product, and the low s...

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Bibliographic Details
Main Authors: Daniel Alejandro Caballero Cerbon, Dirk Weuster-Botz
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-025-02715-y
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