Accessing Promising Passerini Adducts in Anticancer Drug Design

Accessing Promising Passerini Adducts in Anticancer Drug Design

The 3-component Passerini reaction (3CPR), discovered little more than 100 years ago, has been demonstrated in the last few decades to be a valuable tool for accessing structural diversity and complexity, essential topics to consider in drug discovery programs. Focusing on accessing a fine-tuned fam...

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Bibliographic Details
Main Authors:	Ana Margarida Janeiro, Aday González-Bakker, José M. Padrón, Carolina S. Marques
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Series:	Molecules
Subjects:	Passerini-3C oxindole isatin cancer GI<sub>50</sub> drug design
Online Access:	https://www.mdpi.com/1420-3049/29/23/5538
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