Accessing Promising Passerini Adducts in Anticancer Drug Design

Accessing Promising Passerini Adducts in Anticancer Drug Design

The 3-component Passerini reaction (3CPR), discovered little more than 100 years ago, has been demonstrated in the last few decades to be a valuable tool for accessing structural diversity and complexity, essential topics to consider in drug discovery programs. Focusing on accessing a fine-tuned fam...

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Bibliographic Details
Main Authors: Ana Margarida Janeiro, Aday González-Bakker, José M. Padrón, Carolina S. Marques
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
Passerini-3C
oxindole
isatin
cancer
GI<sub>50</sub>
drug design
Online Access:https://www.mdpi.com/1420-3049/29/23/5538
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