Development of a standardized and reproducible murine femoral distraction osteogenesis model

Development of a standardized and reproducible murine femoral distraction osteogenesis model

Objective: Distraction osteogenesis (DO) has been widely used to treat bone defects as its effectiveness in bone regeneration. Currently, distraction devices for establishing DO models are mainly developed for rats or large animals. However, a mouse DO model is in great need for in-depth mechanistic...

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Main Authors: Yuejun Lin, Zhaowei Jiang, Jiaming Yang, Ming Wang, Haixing Wang, Xiaoting Zhang, Xuan Lu, Shanshan Bai, Tongzhou Liang, Botai Li, Jie Shao, Lu Zhang, Dashuang Gao, Jiajun Chen, Sien Lin, Fan Yang, Gang Li
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Orthopaedic Translation
Subjects:
Distraction osteogenesis
External fixators
Limb lengthening
Mouse model
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X24000871
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