Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression
BackgroundIsowighteone, an isoflavonoid compound derived from Ficus hispida L.f. (F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. However, its anti-inflammatory role in vascular calcification is unclear.ObjectWe investigated the efficacy of isowight...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2025.1636883/full |
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