scPair: Boosting single cell multimodal analysis by leveraging implicit feature selection and single cell atlases

Abstract Multimodal single-cell assays profile multiple sets of features in the same cells and are widely used for identifying and mapping cell states between chromatin and mRNA and linking regulatory elements to target genes. However, the high dimensionality of input features and shallow sequencing...

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Bibliographic Details
Main Authors: Hongru Hu, Gerald Quon
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53971-2
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