Efficient protein depletion by genetically controlled deprotection of a dormant N‐degron

Abstract Methods that allow for the manipulation of genes or their products have been highly fruitful for biomedical research. Here, we describe a method that allows the control of protein abundance by a genetically encoded regulatory system. We developed a dormant N‐degron that can be attached to t...

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Bibliographic Details
Main Authors: Christof Taxis, Gunter Stier, Roberta Spadaccini, Michael Knop
Format: Article
Language:English
Published: Springer Nature 2009-04-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2009.25
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