From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1

From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1

Silent information regulator sirtuin 1 (SIRT1) is an NAD+-dependent deacetylase with potent anti-arterial aging activities. Its protective function in aging-related diseases has been extensively studied. In the microcirculation, SIRT1 plays a crucial role in preventing microcirculatory endothelial s...

Full description

Saved in:

Bibliographic Details
Main Authors:	Martin Law, Pei-Chun Wang, Zhong-Yan Zhou, Yu Wang
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Series:	Pharmaceuticals
Subjects:	microcirculation angiogenesis artery aging capillarization endothelium
Online Access:	https://www.mdpi.com/1424-8247/17/11/1495
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer
by: Sophia Daum, et al.
Published: (2025-01-01)

Unlocking the role of liver sinusoidal endothelial cells: Key players in liver fibrosis: Editorial on “Liver sinusoidal endothelial cell: An important yet often overlooked player in the liver fibrosis”
by: Yasuko Iwakiri
Published: (2024-10-01)

VON WILLEBRAND FACTOR, ANGIODYSPLASIA AND ANGIOGENESIS
by: Anna M. Randi, et al.
Published: (2013-09-01)

Metabolic Syndrome, Kidney-Related Adiposity, and Kidney Microcirculation: Unraveling the Damage
by: Kyu Won Jang, et al.
Published: (2024-11-01)

Impairment of Microcirculation Parameters in Patients with a History of Diabetic Foot Ulcers
by: Julien Vouillarmet, et al.
Published: (2024-12-01)

Near-Infrared Spectroscopy Allows for Monitoring of Bone Fracture Healing via Changes in Oxygenation
by: Cedric Nowicki, et al.
Published: (2024-12-01)

Steroids and Malignancy Increase Local Heparanase and Decrease Markers of Osteoblast Activity in Bone Tissue Microcirculation
by: Keren Asayag, et al.
Published: (2024-11-01)

Evaluation of the effect of hemodynamic factors on retinal microcirculation by using 3D confocal image-based computational fluid dynamics
by: Chi Wei Ong, et al.
Published: (2024-11-01)

Tiny clue reveals the general trend: a bibliometric and visualized analysis of renal microcirculation
by: Bing Wang, et al.
Published: (2024-12-01)

Quantitative indicators of microcirculation of the skin of the lower extremities
by: V. I. Rusin, et al.
Published: (2020-12-01)

Early sublingual microcirculation changes in patients with septic shock at different altitudes
by: HE Zongzhao, WANG Hao*, GUO Litao, MA Siqing, XIANG Hui, ZHENG Xing
Published: (2024-11-01)

Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction
by: Xiaolong Qu, et al.
Published: (2025-01-01)

Ultrastructural changes in the common carotid artery in terms of age and gender-related in Rat model
by: Nejat Ünlükal
Published: (2025-02-01)

A New Approach to Non-Invasive Microcirculation Monitoring: Quantifying Capillary Refill Time Using Oximetric Pulse Waves
by: Yuxiang Xia, et al.
Published: (2025-01-01)

Diminished retinal microcirculation in mild preeclampsia without obvious retinopathy in high-altitude native Tibetans by OCTA
by: Chong Tang, et al.
Published: (2024-12-01)

Corneal Endothelial Microscopy: Does a Manual Recognition of the Endothelial Cells Help the Morphometric Analysis Compared to a Fully Automatic Approach?
by: Giulia Carlotta Rizzo, et al.
Published: (2024-10-01)

Visual Recovery and Endothelial Repopulation after DMEK Graft Removal and Vitrectomy for Late Endophthalmitis: A Case Report
by: Eszter Szalai, et al.
Published: (2024-10-01)

Evaluation of wound temperature monitoring at various anatomical sites in the management of patients with diabetic foot undergoing microcirculation reconstruction
by: Hong Liu, et al.
Published: (2024-11-01)

INFLUENCE OF MICROBIAL WOUND DISSEMINATION AND MICROCIRCULATION ON THE RESULTS OF SKIN ENGRAFTMENT
by: Yu. V. Yurova, et al.
Published: (2018-01-01)

Correction of microcirculation disorders in diseases of digestion organs of professional etiology in the rehabilitation period in mutimorbid patients.
by: N. N. Surmilo, et al.
Published: (2018-10-01)

Soluble P-Selectin as an Indicator of Cutaneous Microangiopathy in Uncomplicated Young Patients with Type 1 Diabetes
by: Jolanta Neubauer-Geryk, et al.
Published: (2024-12-01)

Leukotrienes E4 and B4 and vascular endothelium – New insight into the link between vascular inflammation and peripheral arterial
by: Paweł Maga, et al.
Published: (2024-12-01)

On singularities of capillary surfaces in the absence of gravity
by: V. Roytburd
Published: (1983-01-01)

Protection of liver sinusoidal endothelial cells using different preservation solutions
by: Julia H E Houtzager, et al.
Published: (2025-02-01)

Systemic alpha-1 adrenergic receptor inhibition reduces sperm damage in adult and aging spontaneously hypertensive rats
by: Nicolle R. Machado, et al.
Published: (2024-11-01)

Application of optical coherence tomography angiography to study retinal and choroidal vascular changes in patients with first-time coronary artery stenosis
by: Rongrong Guan, et al.
Published: (2025-02-01)

Endothelial dysfunction in patients with different obesity phenotypes
by: T.V. Sekret, et al.
Published: (2024-09-01)

Mechanistic insights into “Three Methods and Three Acupoints” Tuina therapy for improving spinal microcirculation and motor function in sciatic nerve injury model rats
by: Hanyu Zhang, et al.
Published: (2025-01-01)

A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine
by: Deepa J. Arachchillage, et al.
Published: (2025-01-01)

Urban Microcirculation Traffic Network Planning Method Based on Fast Search Random Tree Algorithm
by: Ning YU
Published: (2024-12-01)

Microcirculatory depth of focus measurement shows reduction of tissue edema by albumin resuscitation in burn patients
by: Olcay Dilken, et al.
Published: (2025-01-01)

Interfacial capillary–gravity short-crested waves
by: Boughazi, Dalila, et al.
Published: (2023-08-01)

Can utilization of the venous-to-arterial carbon dioxide difference improve patient outcomes in cardiogenic shock? A narrative review
by: Oskar Kjærgaard Hørsdal
Published: (2025-02-01)

Near-Infrared Spectroscopy (NIRS) to Assess Infection Complications During the Acute Phase of Acute Pancreatitis
by: Nobutaka Chiba, et al.
Published: (2024-11-01)

An association between the blood perfusion parameters in foot tissues and the severity of arterial occlusion and stenosis in the lower extremities
by: Ksenia A. Krasulina, et al.
Published: (2024-11-01)

Development of a rational composition of a polyenzyme composition in the technology of bioscouring of cotton fabrics
by: Ksenia A. Lenko, et al.
Published: (2024-09-01)

A Reusable Capillary Flow-Driven Microfluidic System for Abscisic Acid Detection Using a Competitive Immunoassay
by: Cristiana Domingues, et al.
Published: (2025-01-01)

Hepatic Microhaemocirculation Dynamics in Experimental Extrahepatic Cholestasis
by: K. Kh. Akhmedov, et al.
Published: (2020-12-01)

Paracetamol metabolism by endothelial cells – Potential mechanism underlying intravenous paracetamol-induced hypotension
by: Johs Dannesboe, et al.
Published: (2025-01-01)

Evaluation of metabolic disorders and aging rates depending on SIRT1 polymorphism in patients with arterial hypertension and subclinical hypothyroidism
by: A.O. Radchenko, et al.
Published: (2022-12-01)