Sodium houttuyfonate inhibits the cariogenic virulence of Streptococcus mutans through the downregulation of VicRK two components pathway

Sodium houttuyfonate inhibits the cariogenic virulence of Streptococcus mutans through the downregulation of VicRK two components pathway

Background Caries is one of the most common diseases worldwide, and Streptococcus mutans is considered to be the primary cariogenic pathogen of dental caries. Sodium houttuyfonate (SH) has showed potential antibacterial effects, however, its actions and mechanisms on S. mutans and cariogenicity rema...

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Bibliographic Details
Main Authors: Yaqi Chi, Ye Wang, Di Fu, Lin Yao, Mingying Wei, Ge Zhou, Guang Yang, Ling Zou, Biao Ren
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Oral Microbiology
Subjects:
Sodium houttuyfonate
Streptococcus mutans
caries
virulence
RNA-seq
two component system (VicRK)
Online Access:https://www.tandfonline.com/doi/10.1080/20002297.2025.2465345
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https://www.tandfonline.com/doi/10.1080/20002297.2025.2465345

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