Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India
Background: Bilateral breast cancer (BBC) is a rare clinical entity with limited data regarding clinicopathological aspects and treatment guidelines. Materials and Methods: This was an observational study of patients diagnosed with BBC from August 2012 to July 2014. Synchronous breast cancers (SBCs)...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2018-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=1;spage=58;epage=61;aulast=Jacob |
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| author | Linu Abraham Jacob Abhishek Anand Kuntegowdanahalli C Lakshmaiah Govind K Babu Dasappa Lokanatha M C Suresh Babu Kadabur N Lokesh Antapura Haleshappa Rudresha L K Rajeev Deepak Koppaka |
| author_facet | Linu Abraham Jacob Abhishek Anand Kuntegowdanahalli C Lakshmaiah Govind K Babu Dasappa Lokanatha M C Suresh Babu Kadabur N Lokesh Antapura Haleshappa Rudresha L K Rajeev Deepak Koppaka |
| author_sort | Linu Abraham Jacob |
| collection | DOAJ |
| description | Background: Bilateral breast cancer (BBC) is a rare clinical entity with limited data regarding clinicopathological aspects and treatment guidelines. Materials and Methods: This was an observational study of patients diagnosed with BBC from August 2012 to July 2014. Synchronous breast cancers (SBCs) was defined as two tumors diagnosed within an interval of 6 months and metachronous breast cancer (MBC) as second cancer diagnosed after 6 months. Results: Out of 750 breast cancer patients seen during a 2-year period, 35 had BBC. Ten patients were diagnosed as SBC whereas 25 patients as MBC. Among patients with MBC, the average time for development of contralateral breast cancer was 5 years. In 8 patients, the contralateral breast cancer was detected mammography whereas rest 27 patients were detected by clinical breast examination. At a median follow-up of 24 months, 23 (66%) patients were disease free, 9 (26%) patients had disease relapse, and 3 (8%) patients succumbed to the progressive disease. Conclusions: Every patient with breast cancer should be regularly followed up with clinical breast examination at a more frequent interval. The role of frequent clinical breast examination appears more than mammography especially beyond 5 years for early detection of contralateral breast cancer. |
| format | Article |
| id | doaj-art-b6dc3da942f94d5280b6d3db79b60fe8 |
| institution | Kabale University |
| issn | 0971-5851 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-b6dc3da942f94d5280b6d3db79b60fe82025-08-20T03:52:04ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512018-01-01391586110.4103/ijmpo.ijmpo_56_17Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South IndiaLinu Abraham JacobAbhishek AnandKuntegowdanahalli C LakshmaiahGovind K BabuDasappa LokanathaM C Suresh BabuKadabur N LokeshAntapura Haleshappa RudreshaL K RajeevDeepak KoppakaBackground: Bilateral breast cancer (BBC) is a rare clinical entity with limited data regarding clinicopathological aspects and treatment guidelines. Materials and Methods: This was an observational study of patients diagnosed with BBC from August 2012 to July 2014. Synchronous breast cancers (SBCs) was defined as two tumors diagnosed within an interval of 6 months and metachronous breast cancer (MBC) as second cancer diagnosed after 6 months. Results: Out of 750 breast cancer patients seen during a 2-year period, 35 had BBC. Ten patients were diagnosed as SBC whereas 25 patients as MBC. Among patients with MBC, the average time for development of contralateral breast cancer was 5 years. In 8 patients, the contralateral breast cancer was detected mammography whereas rest 27 patients were detected by clinical breast examination. At a median follow-up of 24 months, 23 (66%) patients were disease free, 9 (26%) patients had disease relapse, and 3 (8%) patients succumbed to the progressive disease. Conclusions: Every patient with breast cancer should be regularly followed up with clinical breast examination at a more frequent interval. The role of frequent clinical breast examination appears more than mammography especially beyond 5 years for early detection of contralateral breast cancer.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=1;spage=58;epage=61;aulast=JacobBilateral breast cancermetachronous breast cancer issynchronous breast cancer |
| spellingShingle | Linu Abraham Jacob Abhishek Anand Kuntegowdanahalli C Lakshmaiah Govind K Babu Dasappa Lokanatha M C Suresh Babu Kadabur N Lokesh Antapura Haleshappa Rudresha L K Rajeev Deepak Koppaka Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India Indian Journal of Medical and Paediatric Oncology Bilateral breast cancer metachronous breast cancer is synchronous breast cancer |
| title | Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India |
| title_full | Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India |
| title_fullStr | Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India |
| title_full_unstemmed | Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India |
| title_short | Clinicopathological profile and treatment outcomes of bilateral breast cancer: A study from tertiary cancer center in South India |
| title_sort | clinicopathological profile and treatment outcomes of bilateral breast cancer a study from tertiary cancer center in south india |
| topic | Bilateral breast cancer metachronous breast cancer is synchronous breast cancer |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=1;spage=58;epage=61;aulast=Jacob |
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