Circ-PDE1C/miR-766-3p/SGTB axis regulates the IL-1β-induced apoptosis, inflammation and oxidative stress in human chondrocytes
Abstract Background Osteoarthritis (OA) is a common degenerative joint disease. Circular RNA Phosphodiesterase 1 C (circ-PDE1C, hsa_circ_0134111) has participated in the IL-1β-induced chondrocyte damages. The objective of our study was to explore the molecular mechanism of circ-PDE1C. Methods Circ-P...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Advances in Rheumatology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s42358-024-00429-0 |
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