Circ-PDE1C/miR-766-3p/SGTB axis regulates the IL-1β-induced apoptosis, inflammation and oxidative stress in human chondrocytes

Circ-PDE1C/miR-766-3p/SGTB axis regulates the IL-1β-induced apoptosis, inflammation and oxidative stress in human chondrocytes

Abstract Background Osteoarthritis (OA) is a common degenerative joint disease. Circular RNA Phosphodiesterase 1 C (circ-PDE1C, hsa_circ_0134111) has participated in the IL-1β-induced chondrocyte damages. The objective of our study was to explore the molecular mechanism of circ-PDE1C. Methods Circ-P...

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Bibliographic Details
Main Authors: Lixia Gao, Tao He, Qingkui Hu, Yan Ma
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Advances in Rheumatology
Subjects:
Circ-PDE1C
miR-766-3p
SGTB
Chondrocytes
Osteoarthritis
Online Access:https://doi.org/10.1186/s42358-024-00429-0
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