Decreased Extracellular Vesicle Vasorin in Severe Preeclampsia Plasma Mediates Endothelial Dysfunction

Decreased Extracellular Vesicle Vasorin in Severe Preeclampsia Plasma Mediates Endothelial Dysfunction

Background Preeclampsia is a serious pregnancy complication affecting 5% to 8% of pregnancies globally. preeclampsia is a leading cause of maternal and neonatal morbidity and death. Despite its prevalence, the underlying mechanisms of preeclampsia remain unclear. This study investigated the role of...

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Main Authors: Saravanakumar Murugesan, Dylan R. Addis, Hanna Hussey, Mark F. Powell, Lakshmi Saravanakumar, Adam B. Sturdivant, Rachel G. Sinkey, Michelle D. Tubinis, Zachary R. Massey, Chelsi Patton, James A. Mobley, Alan N. Tita, Tamas Jilling, Dan E. Berkowitz
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
extracellular vesicles
human aortic endothelial cells
placental explant culture
preeclampsia
short FMS‐like tyrosine kinase 1
vasorin
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.037242
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https://www.ahajournals.org/doi/10.1161/JAHA.124.037242

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