Selective suppression of influenza A/H5N1 virus replication <i>in vitro</i> using nanocomplexes consisting of siRNA and aminopropylsilanol nanoparticles

Selective suppression of influenza A/H5N1 virus replication <i>in vitro</i> using nanocomplexes consisting of siRNA and aminopropylsilanol nanoparticles

Relevance. Studies on model systems have confirmed the effectiveness of antisense oligonucleotides, including those that contain photoactive groups, for the modification of nucleic acids. However, this strategy has not yet found wide application due to the lack of successful methods for the intracel...

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Bibliographic Details
Main Authors: Marina N. Repkova, Asya S. Levina, Oleg Yu. Mazurkov, Elena V. Makarevich, Ekaterina I. Filippova, Natalya A. Mazurkova, Valentina F. Zarytova
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2024-12-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
aminopropylsilanol nanoparticles
nanocomplexes
sirna
antiviral activity
influenza a/h5n1 virus
Online Access:https://microbiol.crie.ru/jour/article/viewFile/18626/1553
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