Enhanced Localized Periodontitis Treatment with Azithromycin-Loaded Niosomal Thermosensitive Gels

Enhanced Localized Periodontitis Treatment with Azithromycin-Loaded Niosomal Thermosensitive Gels

ABSTRACT: Periodontitis is a chronic inflammatory disease requiring localized drug delivery for sustained therapeutic action. Conventional treatments face challenges such as a rapid drug clearance and poor bioavailability. This study develops and evaluates an azithromycin-loaded niosomal thermorespo...

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Bibliographic Details
Main Authors: Kunchorn Kerdmanee, Chuencheewit Thongsiri, Nuttawut Supachawaroj, Sucharat Limsitthichaikoon
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:OpenNano
Subjects:
azithromycin
IL-1β
niosomes
periodontitis
thermoresponsive gels
TNF-α
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952025000167
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