Tumor-associated neutrophils and macrophages exacerbate antidrug IgG-mediated anaphylactic reaction against an immune checkpoint inhibitor
Background With the increased use of immune checkpoint inhibitors (ICIs), side effects and toxicity are a great concern. Anaphylaxis has been identified as a potential adverse event induced by ICIs. Anaphylaxis is a life-threatening medical emergency. However, the mechanisms and factors that can pot...
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| Main Authors: | Ayu Terui, Tomomi Kokubo, Akihiro Hisaka, Hiroto Hatakeyama, Takahiro Arai, Hiroto Kawashima, Ruiheng Tang, Hirohito Abo, Jotaro Hirakawa, Hidetaka Akita |
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| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-12-01
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| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/10/12/e005657.full |
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