Tumor-associated neutrophils and macrophages exacerbate antidrug IgG-mediated anaphylactic reaction against an immune checkpoint inhibitor

Background With the increased use of immune checkpoint inhibitors (ICIs), side effects and toxicity are a great concern. Anaphylaxis has been identified as a potential adverse event induced by ICIs. Anaphylaxis is a life-threatening medical emergency. However, the mechanisms and factors that can pot...

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Bibliographic Details
Main Authors: Ayu Terui, Tomomi Kokubo, Akihiro Hisaka, Hiroto Hatakeyama, Takahiro Arai, Hiroto Kawashima, Ruiheng Tang, Hirohito Abo, Jotaro Hirakawa, Hidetaka Akita
Format: Article
Language:English
Published: BMJ Publishing Group 2022-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/12/e005657.full
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