The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism.
The structure of the early metabolic network is unknown. Here, we report that when considered together, pentose utilization pathways form all life-essential precursors. We speculate that the chemistry preserved in pentose metabolism could therefore have been a central structural element in early met...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS Biology |
| Online Access: | https://doi.org/10.1371/journal.pbio.3002996 |
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| _version_ | 1841533257088237568 |
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| author | Steffen N Lindner Markus Ralser |
| author_facet | Steffen N Lindner Markus Ralser |
| author_sort | Steffen N Lindner |
| collection | DOAJ |
| description | The structure of the early metabolic network is unknown. Here, we report that when considered together, pentose utilization pathways form all life-essential precursors. We speculate that the chemistry preserved in pentose metabolism could therefore have been a central structural element in early metabolism. |
| format | Article |
| id | doaj-art-b57e2d398e0e48b2b68cdf42dd01423d |
| institution | Kabale University |
| issn | 1544-9173 1545-7885 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Biology |
| spelling | doaj-art-b57e2d398e0e48b2b68cdf42dd01423d2025-01-17T05:30:43ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852025-01-01231e300299610.1371/journal.pbio.3002996The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism.Steffen N LindnerMarkus RalserThe structure of the early metabolic network is unknown. Here, we report that when considered together, pentose utilization pathways form all life-essential precursors. We speculate that the chemistry preserved in pentose metabolism could therefore have been a central structural element in early metabolism.https://doi.org/10.1371/journal.pbio.3002996 |
| spellingShingle | Steffen N Lindner Markus Ralser The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism. PLoS Biology |
| title | The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism. |
| title_full | The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism. |
| title_fullStr | The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism. |
| title_full_unstemmed | The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism. |
| title_short | The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism. |
| title_sort | ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism |
| url | https://doi.org/10.1371/journal.pbio.3002996 |
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