The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism.

The structure of the early metabolic network is unknown. Here, we report that when considered together, pentose utilization pathways form all life-essential precursors. We speculate that the chemistry preserved in pentose metabolism could therefore have been a central structural element in early met...

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Bibliographic Details
Main Authors: Steffen N Lindner, Markus Ralser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002996
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