AMPA/kainate receptor activation within the prelimbic cortex is necessary for incubated cocaine-craving

AMPA/kainate receptor activation within the prelimbic cortex is necessary for incubated cocaine-craving

IntroductionThe incubation of craving is a behavioral phenomenon in which cue-elicited craving increases during a period of drug abstinence. Incubated cocaine-craving is associated with increased extracellular glutamate within the medial prefrontal cortex (mPFC) and this release, particularly within...

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Main Authors: Laura L. Huerta Sanchez, Mirette G. Tadros, Hoa H. T. Doan, Sylvie V. Vo, Sanil R. Chaudhari, Taylor L. Li, Peter B. James, Audrey Y. Na, Fernando J. Cano, Tod E. Kippin, Karen K. Szumlinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Psychiatry
Subjects:
incubation of drug craving
incubation of sucrose craving
prefrontal cortex
AMPA receptors
drug craving
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1627477/full
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https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1627477/full

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