Garlic-Derived Allicin Attenuates Parkinson’s Disease via PKA/p-CREB/BDNF/DAT Pathway Activation and Apoptotic Inhibition

Garlic-Derived Allicin Attenuates Parkinson’s Disease via PKA/p-CREB/BDNF/DAT Pathway Activation and Apoptotic Inhibition

Allicin (ALC), a naturally occurring organosulfur compound derived from garlic (<i>Allium sativum</i>), exhibits potential neuroprotective properties. Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by degeneration of dopaminergic neurons and motor dysfu...

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Bibliographic Details
Main Authors: Wanchen Zeng, Yingkai Wang, Yang Liu, Xiaomin Liu, Zhongquan Qi
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Molecules
Subjects:
allicin
Parkinson’s disease
network pharmacology
apoptosis
Online Access:https://www.mdpi.com/1420-3049/30/15/3265
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